Includes barbiturates (barbs), benzodiazepines (benzos) and sedative-hypnotics. Depressants will put you to sleep, relieve anxiety and muscle spasms, and prevent seizures. Barbiturates are older drugs and include butalbital (Fiorina ® ), phenobarbital, Pentothal ® , Seconal ® and Nembutal ® . You can rapidly develop dependence on and tolerance to barbiturates, meaning you need more and more of them to feel and function normally. This makes them unsafe, increasing the likelihood of coma or death. Benzodiazepines were developed to replace barbiturates, though they still share many of the undesirable side effects. Some examples are Valium ® , Xanax ® , Halcion ® , Ativan ® , Klonopin ® and Restoril ® . Ambien ® and Sonata ® are sedative- hypnotic medications approved for the short-term treatment of insomnia that share many of the properties of benzodiazepines. Other CNS depressants include meprobamate, methaqualone (Quaalude ® ), and the illicit drug GHB.